Dissecting the Membrane Cholesterol Requirement for Mycobacterial Entry into Host Cells

Chem Phys Lipids 189:19-27

2015

The Mycobacterium tuberculosis protein pair PE9 (Rv1088) - PE10 (Rv1089) forms heterodimers and induces macrophage apoptosis through TLR4

Cellular Microbiol 17(11): 1653-1669

2015

Unsaturated Lipid Assimilation by Mycobacteria Requires Auxiliary cis-trans Enoyl CoA Isomerase.

Chemistry & Biology 22, 1577-1587.

2015

Specificity and catalysis hardwired at the RNA-protein interface in a translational proofreading enzyme.

Nature Commun. 6:7552 doi: 10.1038/ncomms8552.

2015

Mutations in the predicted active site of Xanthomonas oryzae pv. oryzae XopQ differentially affect virulence, suppression of host innate immunity and induction of HR in a non-host plant.

Mol. Plant Microbe Interact. 28, 195-206.

2015

Structural organization of the dynein-dynactin complex bound to microtubules.

Nature Structural & Molecular Biology (https://doi.org/10.1038/nsmb.2996)

2015

The Pex1/Pex6 complex is a heterohexameric AAA+ motor with alternating and highly coordinated subunits.

Journal of Molecular Biology (https://doi.org/10.1016/j.jmb.2015.01.019)

2015

Pharmaceutical screen identifies novel target processes for activation of autophagy with a broad translational potential.

Nature Communication. 2015 Oct 27;6:8620. doi: 10.1038/ncomms9620

2015

IRGM governs the core autophagy machinery to conduct antimicrobial defense.

Molecular Cell. Volume 58, Issue 3, p507-521, 7 May,

2015

Mechanism of action of the tuberculosis and Crohn disease risk factor IRGM in autophagy.

Autophagy. 2015 Aug 27:0. PMID: 26313894

2015

A single amino acid change in inhibitory killer cell Ig-like receptor results in constitutive receptor self-association and phosphorylation.

Journal of Immunology

2015

Independent amino acid residues in the S2 pocket of falcipain-3 determine its specificity for P2 residues in substrates.

Mol Biochem Parasitol. 202(2):11-22. doi: 0.1016/j.molbiopara.2015.09.005.

2015

Control of synaptic connectivity in Drosophila by a network of IgSF surface proteins.

Cell163:1770-1782

2015

Complementary Expression of Ig superfamily ligands and receptors in synaptic pairs in the Drosophila visual system.

Cell163:1770-1782

2015

A genetic toolkit for tagging intronicMiMICs containing genes.

eLife4:e08469

2015