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एम मोहम्मद इदरीस

एम मोहम्मद इदरीस

एम मोहम्मद इदरीस

वरिष्ठ प्रधान वैज्ञानिक
बायो -मेकनिज़म्ज़ ऑफ़ रिजेनरेशन
2770
idris[at]ccmb[dot]res[dot]in

शोध में रुचि

मेरी वर्तमान शोध रुचि ज़ेब्राफिश (डैनियो रेरियो), समुद्री कॉर्डेट (एस्किडियन) और इकाइनोडर्म (एस्टेरियस प्रजाति) जैसे वैकल्पिक मॉडल जानवरों का उपयोग करके विकासात्मक जीव विज्ञान और तंत्रिका विज्ञान की जटिलता को समझने में है। मेरी शोध गतिविधि मुख्य रूप से प्रोटिओमिक्स और ट्रांसक्रिप्टोमिक्स दृष्टिकोणों का उपयोग करते हुए इन मॉडल जानवरों में पुनर्जनन और अध:पतन की क्रियाविधि को समझने पर केंद्रित है। ज़ेब्राफिश में उपांगों का पुनर्जनन, एस्किडियन में तंत्रिका ऊतक और एस्टेरियस प्रजाति में भुजाओं का पुनर्जनन मेरी प्रयोगशाला में चल रही कुछ महत्वपूर्ण शोध गतिविधियाँ हैं। मैं ज़ेब्राफिश को मॉडल जानवर के रूप में उपयोग करके स्पिनो सेरिबेलर अटैक्सिया और हंटिंगटन रोग की तरह ट्रिपलेट रिपीट विस्तार के कारण न्यूरोडीजेनेरेशन के आणविक और कार्यात्मक तंत्र को समझने में भी रुचि रखता हूँ।

चयनित प्रकाशन

सक्सेना एस, सिंह एस.के., मीना लक्ष्मी एम.जी., मेघा वी, भट्टी बी, ब्रह्मेन्द्र स्वामी सी.वी., सुंदरम सी.एस., इदरीस एम.एम.. ज़ेब्राफ़िश कॉडल फिन पुनर्जनन का प्रोटिओमिक विश्लेषण। मोल सेल प्रोटिओमिक्स। 2012 जनवरी 25।

सिंह एस.के., सक्सेना एस., मीना लक्ष्मी एम.जी., सक्सेना पी., इदरीस एम.एम.. ज़ेब्राफ़िश डैनियो रेरियो ऑल्फैक्ट्री बल्ब का प्रोटीन प्रोफ़ाइल, दो-आयामी जेल इलेक्ट्रोफोरेसिस मैट्रिक्स-सहायता प्राप्त लेज़र डिसोर्प्शन/आयनाइज़ेशन एमएस/एमएस विश्लेषण पर आधारित। ज़ेब्राफ़िश। 2011 दिसंबर;8(4):183-9।

सक्सेना एस, मीना लक्ष्मी एमजी, मेघा एम, सिंह एसके, सुंदरम सीएस, ब्रह्मेंद्र स्वामी सीवी, इदरीस एमएम (2011) ज़ेब्राफ़िश किडनी का प्रोटिओम प्रोफ़ाइल। जर्नल ऑफ़ प्रोटिओमिक्स।

सिंह एस.के., मीना लक्ष्मी एम.जी., सक्सेना एस., ब्रह्मेंद्र स्वामी सी.वी., इदरीस एम.एम. (2011) ज़ेब्राफ़िश के दुम के पंख पर आधारित एक-आयामी जेल वैद्युतकणसंचलन एलसीएमएस/एमएस और द्वि-आयामी जेल वैद्युतकणसंचलन एमएएलडीआई एमएस/एमएस विश्लेषण का प्रोटिओम प्रोफ़ाइल। जर्नल ऑफ़ सेपरेशन साइंस 34(2), 225-32।

सिंह एस.के., सुंदरम सी.एस., शानबाग एस., इदरीस एम.एम. (2010) 2-डीई माल्डी एमएस/एमएस विश्लेषण पर आधारित ज़ेब्राफ़िश मस्तिष्क का प्रोटिओमिक प्रोफ़ाइल। ज़ेब्राफ़िश 7(2) 169-177।

शिक्षा और अनुभव

स्नातकोत्तर:

जैव रसायन विज्ञान; मद्रास विश्वविद्यालय; 1998

Ph.D:

सिओना इंटेस्टाइनलिस में हंटिंग्टिन का विकास, आनुवंशिकी और कार्य; स्टेशन जूलॉजिका \’ए. डोहर्न; 2008

टीम सदस्य

team-members-pic
M Mohammed Idris
M Mohammed Idris

Scientist-G

Scientist-G

PV Athira
PV Athira

Project Associate I

Project Associate I

प्रकाशन

शीर्षक

पत्रिका

वर्ष

A Proteomic perspective and involvement of cytokines in SARS-CoV-2 infection
PLoS One
2023
Defensins: Attractive therapeutic molecules with potential to treat SARS-CoV-2 infection
Indian Journal of Medical Research
2022
Down regulation of Defensin genes in SARS-CoV-2 infection.
Acta Virologica
2022
Transcriptomic and Proteomic insights into patulin mycotoxin-induced cancer-like phenotypes in normal intestinal epithelial cells
Molecular and Cellular Biochemistry
2022
Gramicidin S and Melittin ‑ Potential anti‑viral therapeutic peptides to treat SARS‑CoV‑2 infection
Scientific Reports
2022
Understanding the complexity of epimorphic regeneration in zebrafish: A Transcriptomic and Proteomic approach.
Genomics
2022
Chronic stress induced mood disorders in zebrafish: phenotypic characterization with underlying proteome changes
Pharmacology, Biochemistry and Behavior
2021
Transcriptomic and Proteomic analysis of Hemidactylus frenatus during initial stages of tail regeneration
Scientific Reports
2021
Functional role of Annexins in Zebrafish Caudal fin regeneration - A Gene knockdown approach in regenerating tissue
Biochimie 175: 125-31.
2020
Toxicity of TiO2, SiO2, ZnO, CuO, Au and Ag engineered nanoparticles on hatching and early nauplii of Artemia sp.
Peer J 6: e6138
2019
Role of Annexin gene and its regulation during zebrafish caudal fin regeneration.
Wound, Repair and Regen. 24(3): 551-9.
2016
Qauntitative proteomic analysis of normal and degenerated human intervertebral disc.
Spine J. 16(8): 989-1000.
2016
MPTP induced Parkinson\\\'s disease in zebrafish.
Proteomics. 16(9): 1407-20.
2016
Transcriptomic and proteomic analyses of Amphiura filiformis arm tissue-undergoing regeneration.
J Proteomics 112: (113-24).
2015
Proteomic and gene expression analysis of zebrafish brain undergoing continuous light/dark stress.
J Sleep Res. 24(4): 458-65.
2015
Proteome map of the neural complex of the Tunicate Ciona intestinalis, the closest living relative to vertebrates
Proteomics
2013
Chronic Unpredictable Stress (CUS)-Induced Anxiety and Related Mood Disorders in a Zebrafish Model: Altered Brain Proteome Profile Implicates Mitochondrial Dysfunction
PLOS One
2013
Evidence for dynamic and multiple roles for huntingtin in Ciona intestinalis.
Invertebrate Neuroscience
2013
Proteomic analysis of zebrafish caudal fin regeneration.
Molecular and Cellular Proteomics
2012
Proteome profile of zebrafish kidney
Journal of Proteomics
2011
Proteome profile of zebrafish caudalfin based on one-dimensional gelelectrophoresis LCMS/MS andtwo-dimensional gel electrophoresisMALDI MS/MS analysis
Journal of separation science
2011
Proteome Profile of Zebrafish Danio rerio Olfactory Bulb Based on Two-Dimensional Gel Electrophoresis Matrix-Assisted Laser Desorption/Ionization MS/MS Analysis.
Zebrafish
2011
Synthesis of readily accessible triazole linked dimer deoxynucleoside phophoramidite for sold phase oligonucleotide synthesis. Synthesis
Journal of synthetic organic chemistry
2010
Novel helical foldamers: Organized heterogeneous backbone folding in 1:1 a/Nucleoside-derived-b-amino acid sequences.
Chemical communications
2010
Streptomyces hyderabadensis sp. Nov., a novel actinomycete isolated from soil in Andhra Pradesh, India
International Journal of Systemic and Evolutionary Microbiology
2010
Proteome profile of zebrafish brain based on gel LC-ESI MS/MS analysis
Journal of Proteomics and Bioinformatics
2010
Streptomyces osmaniensis sp. nov., a novel streptomycetes from soil in south India
International Journal of Systemic and Evolutionary Microbiology
2009
The Sea Urchin Genome Sequencing Consortium. The Genome of the Sea Urchin Strongylocentrotus purpuratus.
Science
2006
Proteomic Insights into small molecule modulation on caudal fin regeneration in zebrafish
ACS Omega
2025
Exploration of phosphoproteomic association during epimorphic regeneration.
Scientific Reports
2025
Exploration of phosphoproteomic association during epimorphic regeneration.
Scientific Reports
2025
Exploration of phosphoproteomic association during epimorphic regeneration.
Scientific Reports
2025
Proteomic Insights into small molecule modulation on caudal fin regeneration in zebrafish
ACS Omega
2025
Proteomic Insights into small molecule modulation on caudal fin regeneration in zebrafish
ACS Omega
2025
The Sea Urchin Genome Sequencing Consortium. The Genome of the Sea Urchin Strongylocentrotus purpuratus.
Science
2006
The Sea Urchin Genome Sequencing Consortium. The Genome of the Sea Urchin Strongylocentrotus purpuratus.
Science
2006
Streptomyces osmaniensis sp. nov., a novel streptomycetes from soil in south India
International Journal of Systemic and Evolutionary Microbiology
2009
Streptomyces osmaniensis sp. nov., a novel streptomycetes from soil in south India
International Journal of Systemic and Evolutionary Microbiology
2009
Proteome profile of zebrafish brain based on gel LC-ESI MS/MS analysis
Journal of Proteomics and Bioinformatics
2010
Proteome profile of zebrafish brain based on gel LC-ESI MS/MS analysis
Journal of Proteomics and Bioinformatics
2010
Streptomyces hyderabadensis sp. Nov., a novel actinomycete isolated from soil in Andhra Pradesh, India
International Journal of Systemic and Evolutionary Microbiology
2010
Streptomyces hyderabadensis sp. Nov., a novel actinomycete isolated from soil in Andhra Pradesh, India
International Journal of Systemic and Evolutionary Microbiology
2010
Novel helical foldamers: Organized heterogeneous backbone folding in 1:1 a/Nucleoside-derived-b-amino acid sequences.
Chemical communications
2010
Novel helical foldamers: Organized heterogeneous backbone folding in 1:1 a/Nucleoside-derived-b-amino acid sequences.
Chemical communications
2010
Synthesis of readily accessible triazole linked dimer deoxynucleoside phophoramidite for sold phase oligonucleotide synthesis. Synthesis
Journal of synthetic organic chemistry
2010
Synthesis of readily accessible triazole linked dimer deoxynucleoside phophoramidite for sold phase oligonucleotide synthesis. Synthesis
Journal of synthetic organic chemistry
2010
Proteome Profile of Zebrafish Danio rerio Olfactory Bulb Based on Two-Dimensional Gel Electrophoresis Matrix-Assisted Laser Desorption/Ionization MS/MS Analysis.
Zebrafish
2011
Proteome Profile of Zebrafish Danio rerio Olfactory Bulb Based on Two-Dimensional Gel Electrophoresis Matrix-Assisted Laser Desorption/Ionization MS/MS Analysis.
Zebrafish
2011
Proteome profile of zebrafish caudalfin based on one-dimensional gelelectrophoresis LCMS/MS andtwo-dimensional gel electrophoresisMALDI MS/MS analysis
Journal of separation science
2011
Proteome profile of zebrafish caudalfin based on one-dimensional gelelectrophoresis LCMS/MS andtwo-dimensional gel electrophoresisMALDI MS/MS analysis
Journal of separation science
2011
Proteome profile of zebrafish kidney
Journal of Proteomics
2011
Proteome profile of zebrafish kidney
Journal of Proteomics
2011
Proteomic analysis of zebrafish caudal fin regeneration.
Molecular and Cellular Proteomics
2012
Proteomic analysis of zebrafish caudal fin regeneration.
Molecular and Cellular Proteomics
2012
Evidence for dynamic and multiple roles for huntingtin in Ciona intestinalis.
Invertebrate Neuroscience
2013
Evidence for dynamic and multiple roles for huntingtin in Ciona intestinalis.
Invertebrate Neuroscience
2013
Chronic Unpredictable Stress (CUS)-Induced Anxiety and Related Mood Disorders in a Zebrafish Model: Altered Brain Proteome Profile Implicates Mitochondrial Dysfunction
PLOS One
2013
Chronic Unpredictable Stress (CUS)-Induced Anxiety and Related Mood Disorders in a Zebrafish Model: Altered Brain Proteome Profile Implicates Mitochondrial Dysfunction
PLOS One
2013
Proteome map of the neural complex of the Tunicate Ciona intestinalis, the closest living relative to vertebrates
Proteomics
2013
Proteome map of the neural complex of the Tunicate Ciona intestinalis, the closest living relative to vertebrates
Proteomics
2013
Proteomic and gene expression analysis of zebrafish brain undergoing continuous light/dark stress.
J Sleep Res. 24(4): 458-65.
2015
Proteomic and gene expression analysis of zebrafish brain undergoing continuous light/dark stress.
J Sleep Res. 24(4): 458-65.
2015
Transcriptomic and proteomic analyses of Amphiura filiformis arm tissue-undergoing regeneration.
J Proteomics 112: (113-24).
2015
Transcriptomic and proteomic analyses of Amphiura filiformis arm tissue-undergoing regeneration.
J Proteomics 112: (113-24).
2015
MPTP induced Parkinson\\\\\\\'s disease in zebrafish.
Proteomics. 16(9): 1407-20.
2016
MPTP induced Parkinson\\\\\\\'s disease in zebrafish.
Proteomics. 16(9): 1407-20.
2016
Qauntitative proteomic analysis of normal and degenerated human intervertebral disc.
Spine J. 16(8): 989-1000.
2016
Qauntitative proteomic analysis of normal and degenerated human intervertebral disc.
Spine J. 16(8): 989-1000.
2016
Role of Annexin gene and its regulation during zebrafish caudal fin regeneration.
Wound, Repair and Regen. 24(3): 551-9.
2016
Role of Annexin gene and its regulation during zebrafish caudal fin regeneration.
Wound, Repair and Regen. 24(3): 551-9.
2016
Toxicity of TiO2, SiO2, ZnO, CuO, Au and Ag engineered nanoparticles on hatching and early nauplii of Artemia sp.
Peer J 6: e6138
2019
Toxicity of TiO2, SiO2, ZnO, CuO, Au and Ag engineered nanoparticles on hatching and early nauplii of Artemia sp.
Peer J 6: e6138
2019
Functional role of Annexins in Zebrafish Caudal fin regeneration - A Gene knockdown approach in regenerating tissue
Biochimie 175: 125-31.
2020
Functional role of Annexins in Zebrafish Caudal fin regeneration - A Gene knockdown approach in regenerating tissue
Biochimie 175: 125-31.
2020
Transcriptomic and Proteomic analysis of Hemidactylus frenatus during initial stages of tail regeneration
Scientific Reports
2021
Transcriptomic and Proteomic analysis of Hemidactylus frenatus during initial stages of tail regeneration
Scientific Reports
2021
Chronic stress induced mood disorders in zebrafish: phenotypic characterization with underlying proteome changes
Pharmacology, Biochemistry and Behavior
2021
Chronic stress induced mood disorders in zebrafish: phenotypic characterization with underlying proteome changes
Pharmacology, Biochemistry and Behavior
2021
Understanding the complexity of epimorphic regeneration in zebrafish: A Transcriptomic and Proteomic approach.
Genomics
2022
Understanding the complexity of epimorphic regeneration in zebrafish: A Transcriptomic and Proteomic approach.
Genomics
2022
Gramicidin S and Melittin ‑ Potential anti‑viral therapeutic peptides to treat SARS‑CoV‑2 infection
Scientific Reports
2022
Gramicidin S and Melittin ‑ Potential anti‑viral therapeutic peptides to treat SARS‑CoV‑2 infection
Scientific Reports
2022
Transcriptomic and Proteomic insights into patulin mycotoxin-induced cancer-like phenotypes in normal intestinal epithelial cells
Molecular and Cellular Biochemistry
2022
Transcriptomic and Proteomic insights into patulin mycotoxin-induced cancer-like phenotypes in normal intestinal epithelial cells
Molecular and Cellular Biochemistry
2022
Down regulation of Defensin genes in SARS-CoV-2 infection.
Acta Virologica
2022
Down regulation of Defensin genes in SARS-CoV-2 infection.
Acta Virologica
2022
Defensins: Attractive therapeutic molecules with potential to treat SARS-CoV-2 infection
Indian Journal of Medical Research
2022
Defensins: Attractive therapeutic molecules with potential to treat SARS-CoV-2 infection
Indian Journal of Medical Research
2022
A Proteomic perspective and involvement of cytokines in SARS-CoV-2 infection
PLoS One
2023
A Proteomic perspective and involvement of cytokines in SARS-CoV-2 infection
PLoS One
2023

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